Lydia Email Agent is a small, fast windows program that monitors up to 15 email accounts.
Lydia not only notifies you when new email arrives but also filters spam, lets you read and reply to email and delete unwanted email. Lydia includes aggressive spam filtering to keep out unwanted email. Lydia also includes advanced features such as multiple SMTP settings, SMTP authentication, spell check and the ability to send email file attachments.

Email Notification POP3 spam filter